Antibiotic treatment shapes antigen presentation during chronic TB infection, offering novel targets for therapeutic vaccination
Y.-M. Chuang, N. K. Dutta, M. L. Pinn, C.-F. Hung, P. C. Karakousis
This study shows that antibiotic treatment alters antigen presentation during TB, and therapeutic vaccination targeting RelMtb enhances isoniazid efficacy against Mtb persisters.
bioRxiv · May 15, 2019Microbiology