Author

N. K. Dutta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C.-F. Hung· 1 shared H. Salamon· 1 shared K. Yamaguchi· 1 shared M. L. Gennaro· 1 shared M. L. Pinn· 1 shared N. Bruiners· 1 shared P. C. Karakousis· 1 shared P. Karakousis· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

C.-F. Hung

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The anti-tubercular activity of simvastatin is mediated by cholesterol-dependent regulation of autophagy via the AMPK-mTORC1-TFEB axis

N. Bruiners, N. K. Dutta, V. Guerrini, H. Salamon, K. Yamaguchi, P. Karakousis, M. L. Gennaro

This study shows simvastatin's anti-tubercular effect is due to cholesterol inhibition, which activates AMPK, blocks mTORC1, and promotes TFEB-driven autophagy.

bioRxiv · Mar 4, 2020Immunology

Antibiotic treatment shapes antigen presentation during chronic TB infection, offering novel targets for therapeutic vaccination

Y.-M. Chuang, N. K. Dutta, M. L. Pinn, C.-F. Hung, P. C. Karakousis

This study shows that antibiotic treatment alters antigen presentation during TB, and therapeutic vaccination targeting RelMtb enhances isoniazid efficacy against Mtb persisters.

bioRxiv · May 15, 2019Microbiology