I. I. Davydov

Tumor-agnostic transcriptome-based classifier identifies spatial infiltration patterns of CD8+ T cells in the tumor microenvironment and predicts clinical outcome in early- and late-phase clinical trials

This study develops a transcriptome-based classifier to predict CD8+ T cell spatial infiltration patterns in the tumor microenvironment and shows its prognostic and predictive value across clinical trials.

Detection of pathways affected by positive selection in primate lineages ancestral to humans

The paper detects pathways affected by positive selection in primate lineages ancestral to humans, identifying significant signals in immune response, sensory perception, metabolism, and energy production.