K. Korski

Tumor-agnostic transcriptome-based classifier identifies spatial infiltration patterns of CD8+ T cells in the tumor microenvironment and predicts clinical outcome in early- and late-phase clinical trials

This study develops a transcriptome-based classifier to predict CD8+ T cell spatial infiltration patterns in the tumor microenvironment and shows its prognostic and predictive value across clinical trials.

Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells

The paper assesses oncogenic risk of Pim-1 kinase overexpression in c-kit+ cardiac interstitial cells using multiple assays and finds no evidence of oncogenic phenotype.