Author

M. L. Simpson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. P. Collier· 2 shared P. M. Caveney· 2 shared R. M. Dabbs· 2 shared W. T. McClintic· 2 shared G. Chauhan· 1 shared L. S. Weinberger· 1 shared M. M. K. Hansen· 1 shared R. V. Desai· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

C. P. Collier

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Adsorption of semiflexible polymers in crowded environments

G. Chauhan, M. L. Simpson, S. M. Abel

This study uses simulations to show that crowding increases adsorption of semiflexible polymers on repulsive surfaces, with effects dependent on polymer stiffness, crowder size, and volume fraction.

bioRxiv · Apr 22, 2021Biophysics

Molecular Transport across Lipid Membranes Controls Cell-Free Expression Level and Dynamics

P. M. Caveney, R. M. Dabbs, W. T. McClintic, C. P. Collier, M. L. Simpson

The paper shows how external resource availability and membrane transport properties influence protein expression levels and dynamics in permeable lipid vesicles.

bioRxiv · Apr 12, 2019 · PreprintBiophysics

Controlling Cell-Free Gene Expression Behavior by Tuning Membrane Transport Properties

P. M. Caveney, R. M. Dabbs, W. T. McClintic, S. E. Norred, C. P. Collier, M. L. Simpson

This paper demonstrates an optical treatment method that reduces membrane permeability variability in lipid vesicles, enhancing gene expression consistency and levels.

bioRxiv · Apr 10, 2019 · PreprintBiophysics

Cytoplasmic import and processing of mRNA amplify transcriptional bursts accounting for the majority of cellular noise

M. M. K. Hansen, R. V. Desai, M. L. Simpson, L. S. Weinberger

The paper shows that cytoplasmic mRNA processing amplifies transcriptional bursts, contributing to most cellular noise in both human and mouse cells.

bioRxiv · Dec 13, 2017Cell Biology