Author

L. S. Weinberger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. M. K. Hansen· 2 shared A. Lex· 1 shared B. K. Lohman· 1 shared B. S. Razooky· 1 shared C. Chin· 1 shared C. Stubben· 1 shared D. Grossman· 1 shared D. Lange· 1 shared

Activity by Year

2017-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

M. M. K. Hansen

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Author profile →

4 papers

Recent·Most cited

Bidirectional interconversion between mutually exclusive tumorigenic and drug-tolerant melanoma cell phenotypes

Y. Zhang, R. L. Belote, M. A. Urquijo, M. M. Hansen, M. Hejna, T. E. Moustafa, T. Liu, D. Lange, F. Vand-Rajabpour, M. Chang, B. K. Lohman, C. Stubben, X. Zhang, L. S. Weinberger, M. W. VanBrocklin, , R. L. Judson-Torres

This study identifies bidirectional interconversion between tumorigenic and drug-tolerant melanoma cell states through BRN2 expression, revealing distinct molecular programs and therapeutic implications.

bioRxiv · Aug 26, 2020 · PreprintCancer Biology

Cytoplasmic import and processing of mRNA amplify transcriptional bursts accounting for the majority of cellular noise

M. M. K. Hansen, R. V. Desai, M. L. Simpson, L. S. Weinberger

The paper shows that cytoplasmic mRNA processing amplifies transcriptional bursts, contributing to most cellular noise in both human and mouse cells.

bioRxiv · Dec 13, 2017Cell Biology

A Feedback Motif that Breaks the Fundamental Limit on Noise Suppression to Stabilize Fate

W. Y. Wen, E. Ingerman, M. M. K. Hansen, B. S. Razooky, R. D. Dar, C. Chin, M. Simpson, L. S. Weinberger

The paper identifies a feedback motif in HIV that suppresses noise more effectively than traditional methods, stabilizing cellular commitment to the active-replication state.

bioRxiv · Jun 9, 2017Cell Biology

Transient Thresholding: A Mechanism Enabling Non-Cooperative Transcriptional Circuitry To Form A Switch

K. H. Aull, E. Tanner, M. Thomson, L. S. Weinberger

The paper identifies a transient activation threshold in the HIV Tat circuit that enables temporary latency despite lacking cooperativity and deterministic bistability.

bioRxiv · May 10, 2017Biophysics