Author

M. Lipka-Lloyd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Organism:human· 1

Frequent Co-Authors

B. D. Bax· 2 shared A. J. Warren· 1 shared E. Mahenthiralingam· 1 shared H. Morgan· 1 shared J. Holmes· 1 shared K. T. Elvers· 1 shared N. Hughes· 1 shared N. P. Burton· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

B. D. Bax

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2 papers

Recent·Most cited

A 2.8A structure of zoliflodacin in a DNA-cleavage complex with Staphylococcus aureus DNA gyrase

H. Morgan, M. Lipka-Lloyd, A. J. Warren, N. Hughes, J. Holmes, N. P. Burton, E. Mahenthiralingam, B. D. Bax

This paper reports the 2.8Å X-ray structure of zoliflodacin bound to Staphylococcus aureus DNA gyrase, showing its mechanism of DNA cleavage inhibition and improved antibacterial activity.

bioRxiv · Nov 30, 2022 · PreprintBiophysics

Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains

K. T. Elvers, M. Lipka-Lloyd, R. C. Trueman, B. D. Bax, Y. Mehellou

The paper determines the crystal structures of human SPAK and OSR1 CCT domains and measures their binding affinity to a WNK4 peptide, providing a basis for designing inhibitors targeting SPAK-activation.

bioRxiv · Aug 19, 2021Biochemistry