Opposing effects of acellular and whole cell pertussis vaccines on Bordetella pertussis biofilm formation, Siglec-F+ neutrophil recruitment and bacterial clearance in mouse nasal tissues
J. M. Hall, J. L. Gutierrez-Ferman, M. M. Shamseldin, M. M. Guo, Y. A. Gupta, R. Deora, P. Dubey
This study compares the effects of acellular and whole cell pertussis vaccines on Bp biofilm formation, neutrophil recruitment, and bacterial clearance in mouse nasal tissues, showing opposing impacts on bacterial persistence and immune response.
bioRxiv · Jan 23, 2024 · PreprintImmunology