P. Dubey

Modelling Amoebic Brain Infection Caused by Balamuthia mandrillaris Using a Human Cerebral Organoid

This paper uses human cerebral organoids to model Balamuthia mandrillaris infection, revealing host responses, biomarkers, and the therapeutic potential of nitroxoline.

Opposing effects of acellular and whole cell pertussis vaccines on Bordetella pertussis biofilm formation, Siglec-F+ neutrophil recruitment and bacterial clearance in mouse nasal tissues

This study compares the effects of acellular and whole cell pertussis vaccines on Bp biofilm formation, neutrophil recruitment, and bacterial clearance in mouse nasal tissues, showing opposing impacts on bacterial persistence and immune response.

Leveraging RAS-mSIN1 Interaction to Selectively Inhibit mTORC2 Employing Competitive RAS Binding Peptide: Implications in Breast Cancer Metastasis

The paper withdraws a manuscript due to incomplete experiments and requests that it not be cited as a reference.

Prime-pull immunization of mice with a BcfA-adjuvanted vaccine elicits mucosal immunity and prevents SARS CoV-2 infection and pathology

Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen.

Evaluation of Correlation between CD44, Radiotherapy Response and Survival Rate in Patients with Advanced Stage of Head and Neck Squamous Cell Carcinoma (HNSCC)

The novel leishmanial Copper P-type ATPase plays a vital role in intracellular parasite survival

This study identifies and characterizes the Leishmania major Cu-ATPase, LmATP7, and demonstrates its role in copper stress resistance and parasite survival within macrophages.

Nanoscale indentation of plasma membrane establishes a contractile actomyosin scaffold through selective activation of the Amphiphysin-Rho1-Dia/DAAM and Rok pathway

The paper shows that nanoscale stretching of the plasma membrane recruits Amphiphysin and Rho1, leading to actomyosin scaffold formation that clamps spermatid heads.

Cardiomyocyte Contractile Impairment in Heart Failure Results from Reduced BAG3-mediated Sarcomeric Protein Turnover

The paper shows reduced BAG3-mediated sarcomere turnover causes cardiomyocyte contractile impairment in heart failure, with gene therapy restoring function in mice.

Bordetella Colonization Factor A (BcfA) elicits protective immunity against Bordetella bronchiseptica in the absence of an additional adjuvant

This study shows that BcfA can act as both an antigen and adjuvant, providing protection against B. bronchiseptica without additional adjuvants.

Atypical septate junctions maintain the somatic enclosure around maturing spermatids and prevent premature sperm release in Drosophila testis.

The paper shows that septate junctions maintain the somatic enclosure around maturing spermatids in Drosophila testis, preventing premature sperm release and ensuring proper fertility.