Author

M. Mahoney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. W. Janetka· 2 shared A. C. Boon· 1 shared A. E. Mayer Bridwell· 1 shared A. J. O'Donoghue· 1 shared A. L. Lourenco· 1 shared A. M. Klinger· 1 shared B. V. Troan· 1 shared C. E. Thompson· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

J. W. Janetka

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Efficacy of Host Cell Serine Protease Inhibitor MM3122 against SARS-CoV-2 for Treatment and Prevention of COVID-19

A. C. Boon, T. L. Bricker, E. J. Fritch, S. R. Leist, K. L. Gully, R. S. Baric, R. Graham, B. V. Troan, M. Mahoney, J. W. Janetka

This paper demonstrates that MM3122, a host cell serine protease inhibitor, effectively inhibits SARS-CoV-2 replication and reduces disease severity in mice, both prophylactically and therapeutically.

Journal of Virology · May 14, 2024Peer-reviewedMicrobiology

A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

M. Mahoney, V. C. Damalanka, M. Tartell, D. H. Chung, A. L. Lourenco, D. Pwee, A. E. Mayer Bridwell, M. Hoffmann, J. Voss, P. Karmakar, N. P. Azouz, A. M. Klinger, P. W. Rothlauf, C. E. Thompson, M. Lee, , J. W. Janetka

This paper identifies a novel class of TMPRSS2 inhibitors that effectively block SARS-CoV-2 and MERS-CoV entry and show promise as a therapeutic for COVID-19.

bioRxiv · May 6, 2021Microbiology