Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses
J. Pansieri, I. A. Iashchishyn, H. Fakhouri, L. Ostojic, M. Malisauskas, G. Musteikyte, V. Smirnovas, M. M. Schneider, T. Scheidt, C. K. Xu, G. Meisl, T. P. Knowles, E. Gazit, R. Antoine, L. Morozova-Roche
The paper investigates the co-aggregation of S100A9 and Aβ42 amyloids using CDMS, microscopy, and kinetic analysis, revealing templating of S100A9 fibrils on Aβ42 surfaces.
bioRxiv · May 26, 2020Biophysics