Author

M. Marcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Andreani· 1 shared C. S. Silva· 1 shared E. Boeri Erba· 1 shared I. Dieryck· 1 shared I. Garcia Ferrer· 1 shared I. Silvestri· 1 shared J. Manigrasso· 1 shared L. Marino Perez· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Andreani

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

biGMamAct: efficient CRISPR/Cas9-mediated docking of large functional DNA cargoes at the ACTB locus

M. Pelosse, M. Marcia

The paper introduces biGMamAct, a system for efficiently integrating large DNA cargoes at the ACTB locus using CRISPR/Cas9, demonstrating its use in expressing multiple fluorescent proteins and visualizing subcellular compartments.

bioRxiv · Apr 18, 2024 · PreprintCell Biology

A previously-unrecognized motif of transcription factor RYBP, hotspot of cancer-related mutations, is essential for the integrity of Polycomb repressive complex 1

C. S. Silva, L. Marino Perez, I. Garcia Ferrer, I. Dieryck, O. Pessey, E. Boeri Erba, M. Ringkjobing Jensen, M. Marcia

This study identifies a critical RYBP motif in vPRC1 essential for complex stability and linked to cancer mutations, using AlphaFold2 and NMR.

bioRxiv · Oct 23, 2023 · PreprintBiochemistry

Targeting the conserved active site of splicing machines with specific and selective small molecule modulators

I. Silvestri, J. Manigrasso, A. Andreani, N. Brindani, M. De Vivo, M. Marcia

This study demonstrates how small molecules interact with the conserved active site of splicing machines, showing their potential for designing splicing modulators targeting both bacterial introns and the human spliceosome.

bioRxiv · Jun 21, 2023Biochemistry