Author

M. McKeague

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:clinical cohort / trial· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Messikommer· 1 shared A. Theocharides· 1 shared B. Maru· 1 shared C. Mingard· 1 shared G. Keller· 1 shared J. Buechel· 1 shared K. Seipel· 1 shared N. W. Luedtke· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Messikommer

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2 papers

Recent·Most cited

Single-nucleotide-resolution genomic maps of O6-methylguanine from the glioblastoma drug temozolomide

J. Buechel, C. Mingard, V. Takhaveev, P. B. Reinert, G. Keller, T. Kloter, S. Huber, M. McKeague, S. J. Sturla

This paper introduces O6-MeG-seq, a method to map O6-methylguanine at single-nucleotide resolution, and shows MGMT does not preferentially repair O6-MeG based on sequence context or chromatin state.

bioRxiv · Dec 12, 2023Cancer Biology

Cancer Prognosis According to Parthanatos Features

A. Messikommer, B. Maru, K. Seipel, P. J. M. Valk, A. Theocharides, T. Pabst, M. McKeague, N. W. Luedtke

This study shows that parthanatos, a PARP-1-mediated cell death pathway, is associated with improved survival in AML patients treated with cytarabine and anthracycline.

bioRxiv · May 24, 2021 · PreprintCancer Biology