Cytotoxicity of 1-deoxysphingolipid Unraveled by Genome-wide Genetic Screens and Lipidomics
A. G. Haribowo, J. T. Hannich, A. H. Michel, M. Megyeri, M. Schuldiner, B. Kornmann, H. Riezman
This study identifies cytotoxic effects of 1-deoxysphingolipid species and reveals mechanisms linking their accumulation to HSAN IA/C pathology through genetic screens and lipidomics.
bioRxiv · Jun 3, 2019Cell Biology