Author

M. Mercadante

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

E. R. Kastenhuber· 2 shared J. L. Johnson· 2 shared L. C. Cantley· 2 shared F. Muecksch· 1 shared G. R. Whittaker· 1 shared J. A. Jaimes· 1 shared R. E. Schwartz· 1 shared T. M. Yaron· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

E. R. Kastenhuber

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2 papers

Recent·Most cited

Evolution of host protease interactions among SARS-CoV-2 variants of concern and related coronaviruses

E. R. Kastenhuber, M. Mercadante, J. L. Johnson, T. M. Yaron, L. C. Cantley

The paper examines how SARS-CoV-2 variants interact with host proteases and shows that some proteases remain effective against variant spike proteins.

bioRxiv · Jun 16, 2022 · PreprintMicrobiology

Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

E. R. Kastenhuber, J. A. Jaimes, J. L. Johnson, M. Mercadante, F. Muecksch, Y. Weisblum, Y. Bram, R. E. Schwartz, G. R. Whittaker, L. C. Cantley

This study shows coagulation factors like factor Xa and thrombin directly cleave SARS-CoV-2 spike, enhancing viral entry, and suggests anticoagulation could reduce infection.

bioRxiv · Mar 31, 2021Microbiology