M. Mhlanga

Multi-omic profiling of pathogen-stimulated primary immune cells

The paper uses long-read sequencing to profile immune cells stimulated by pathogens, identifying novel transcripts and isoforms that reveal new insights into immune response mechanisms.

Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response

This study shows that reducing Lamin-A/C levels enhances pro-inflammatory macrophage responses, and inhibiting its degradation or the IFN-β-STAT pathway can suppress inflammation.