Author

M. Munchhalfen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Singh· 1 shared C. Zhu· 1 shared D. M. Reyes-Aguilar· 1 shared H.-K. Choi· 1 shared J. Lyu· 1 shared J. Wienands· 1 shared R. Gorg· 1 shared S. Travaglino· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

A. Singh

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1 paper

Recent·Most cited

Mechanotransduction governs CD40 function and underlies X-linked Hyper IgM syndrome

H.-K. Choi, S. Travaglino, M. Munchhalfen, R. Gorg, Z. Zhong, J. Lyu, D. M. Reyes-Aguilar, J. Wienands, A. Singh, C. Zhu

This study shows that CD40-CD40L interactions form catch bonds that enhance B cell signaling and antibody class-switch, and mutations in CD40L disrupt this mechanism, causing X-linked Hyper IgM syndrome.

bioRxiv · Jul 23, 2023Immunology