Lesion-specific suppression of YAP/TAZ by biomimetic nanodrug ameliorates atherosclerosis development
H.-C. Huang, T.-Y. Wang, J. Rousseau, M. Mungaray, C. Michaud, C. Plaisier, Z. B. Chen, K.-C. Wang
This paper develops a biomimetic nanodrug targeting YAP/TAZ in atherosclerotic plaques, showing reduced plaque development in mice with minimal off-target effects.
bioRxiv · Apr 24, 2023 · PreprintBioengineering