Author

C. Plaisier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Hawkins-Daarud· 1 shared A. Patel· 1 shared A. R. A. Anderson· 1 shared B. R. Bendok· 1 shared C. Krishna· 1 shared C. Michaud· 1 shared C. Sereduk· 1 shared C. Toledo· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. Hawkins-Daarud

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lesion-specific suppression of YAP/TAZ by biomimetic nanodrug ameliorates atherosclerosis development

H.-C. Huang, T.-Y. Wang, J. Rousseau, M. Mungaray, C. Michaud, C. Plaisier, Z. B. Chen, K.-C. Wang

This paper develops a biomimetic nanodrug targeting YAP/TAZ in atherosclerotic plaques, showing reduced plaque development in mice with minimal off-target effects.

bioRxiv · Apr 24, 2023 · PreprintBioengineering

Mapping multiregional imaging-localized biopsies to MRI habitats reveals biologically significant glioma tissue states and associated patterns of cohabitating cellular subpopulations

L. Curtin, K. M. Bond, P. R. Jackson, A. Hawkins-Daarud, S. Velez, N. Shakir, J. C. Urcuyo, G. De Leon, K. W. Singleton, J. M. Langworthy, K. Clark-Swanson, Y. Lassiter-Morris, L. Paulson, C. Sereduk, C. Krishna, , K. R. Swanson

The paper maps MRI-localized glioma biopsies to MRI habitats, identifying transcriptional tissue states and their association with cellular subpopulations and MRI features.

bioRxiv · Mar 23, 2022 · PreprintCancer Biology

Synthetic Maturation of Multilineage Human Liver Organoids via Genetically Guided Engineering

J. J. Velazquez, R. LeGraw, F. Moghadam, Y. Tan, J. Kilbourne, J. Hislop, S. Liu, D. Cats, S. M. Chuva de Sousa Lopes, C. Plaisier, P. Cahan, S. Kiani, M. R. Ebrahimkhani

This paper demonstrates genetic engineering of liver organoids to enhance maturation and functionality through CRISPR and transcription factor overexpression.

bioRxiv · May 10, 2020Bioengineering

Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma

H. Feldman, C. Toledo, S. Arora, P. Hoellerbauer, P. Corrin, L. Carter, M. Kufeld, H. Bolouri, R. Basom, J. Delrow, J. McFaline-Figueroa, C. Trapnell, S. Pollard, A. Patel, C. Plaisier, P. Paddison

The paper identifies a quiescent-like state, Neural G0, in human neural stem cells and gliomas using scRNA-seq, linking it to tumor aggressiveness and survival.

bioRxiv · Feb 16, 2020 · PreprintCell Biology