High expression of CD38 and MHC class II on CD8+ T cells during severe influenza disease reflects bystander activation and trogocytosis
X. Jia, B. Chua, L. Loh, M. Koutsakos, L. Kedzierski, M. Olshanski, W. Heath, J. Xu, Z. Wang, K. Kedzierska
This study investigates CD38 and MHC-II co-expression on CD8+ T cells during severe influenza, finding that it reflects bystander activation and trogocytosis from antigen-presenting cells, and is important for memory establishment.
Clinical & Translational Immunology · Sep 8, 2021Peer-reviewedImmunology