Autophagy is required to prevent early pro-inflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen replication in macrophages
R. L. Kinsella, J. M. Kimmey, A. Smirnov, R. Woodson, M. R. Gaggioli, S. M. Chavez, D. Kreamalmeyer, C. L. Stallings
This study shows that ATG5 in CD11c+ cells suppresses pro-inflammatory cytokines and neutrophil recruitment during M. tuberculosis infection without affecting pathogen replication.
bioRxiv · Nov 4, 2022 · PreprintImmunology