Author

M. R. Owen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 2 Approach:mechanistic / dynamical model· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

K. R. Swanson· 4 shared L. Curtin· 4 shared A. Hawkins-Daarud· 3 shared K. G. van der Zee· 3 shared A. B. Porter· 2 shared A. Hawkins Daarud· 1 shared A. Stokes· 1 shared B. Morris· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCancer Biology

K. R. Swanson

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Author profile →

4 papers

Recent·Most cited

A Mechanistic Investigation into Ischemia-Driven Distal Recurrence of Glioblastoma

L. Curtin, A. Hawkins-Daarud, A. B. Porter, K. G. van der Zee, M. R. Owen, K. R. Swanson

This study extends a GBM mechanistic model to investigate how ischemia influences distal tumor recurrence by incorporating vascular efficiency and hypoxia.

Bulletin of Mathematical Biology · Nov 7, 2020Peer-reviewedCancer Biology

Modeling the Role of Hypoxia in Glioblastoma Growth and Recurrence Patterns

L. Curtin, A. Hawkins-Daarud, A. B. Porter, M. R. Owen, K. G. van der Zee, K. R. Swanson

This study uses a computational model to show that hypoxic cell migration drives glioblastoma growth and distant recurrence.

bioRxiv · Aug 22, 2020 · PreprintCancer Biology

Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations

B. Morris, L. Curtin, A. Hawkins-Daarud, M. E. Hubbard, R. Rahman, S. J. Smith, D. Auer, N. L. Tran, L. S. Hu, J. M. Eschbacher, K. A. Smith, A. Stokes, K. R. Swanson, M. R. Owen

The paper uses biopsy data and a mechanistic model to study interactions between EGFR and PDGFRA amplified sub-populations in glioblastomas.

bioRxiv · Apr 8, 2020Cancer Biology

Investigating the Role of Hypoxia-Induced Migration in Glioblastoma Growth Rates

L. Curtin, A. Hawkins Daarud, K. G. van der Zee, K. R. Swanson, M. R. Owen

The paper extends the PIHNA model to study how hypoxic and normoxic cell migration rates affect glioblastoma growth wave-speed, identifying a minimum wave-speed and conditions for increased growth.

bioRxiv · Dec 5, 2019Cancer Biology