CD8+ cells and small viral reservoirs facilitate post-ART control of SIV in Mauritian cynomolgus macaques
O. E. Harwood, L. M. Matschke, R. V. Moriarty…·S. L. O'Connor
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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
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O. E. Harwood, L. M. Matschke, R. V. Moriarty…·S. L. O'Connor
O. E. Harwood, A. J. Balgeman, A. J. Weaver…·S. L. O'Connor
This study shows that therapeutic vaccination with a heterologous prime-boost regimen followed by N-803 treatment enhances CD8+ T cell responses in SIV-infected macaques.
J. T. Weinfurter, S. S. D'Souza, L. M. Matschke…·M. R. Reynolds
This study shows that MHC-matched allogeneic bone marrow transplants in ART-suppressed SHIV-infected macaques do not fully eliminate viral reservoirs, with persistent SHIV DNA in tissues and rebound after ART interruption.
J. T. Weinfurter, M. E. Graham, A. J. Ericsen…·M. R. Reynolds
The paper identifies a minor histocompatibility antigen in Mauritian cynomolgus macaques using alloimmunization, exome sequencing, and bioinformatics, showing its potential as a target for HIV immunotherapies.