Balancing the influenza neuraminidase and hemagglutinin responses by exchanging the vaccine virus backbone
J. Gao, H. Wan, X. Li, M. Rakic Martinez, Y. Gao, Z. Ye, R. Daniels
The paper shows that exchanging viral backbone genes can increase neuraminidase content in influenza virions, leading to better NA antibody responses in mice.
bioRxiv · Dec 8, 2020Microbiology