The CMG helicase bypasses DNA protein cross-links to facilitate their repair
J. L. Sparks, A. O. Gao, M. Raschle, N. B. Larsen, M. Mann, J. P. Duxin, J. C. Walter
The paper shows that the CMG helicase bypasses DNA-protein cross-links without prior proteolysis, and RTEL1 aids this process and also promotes proteolysis.
bioRxiv · Jul 31, 2018Biochemistry