Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine show antiviral activity against the novel variants in vitro
M. S. Fred, S. Kuivanen, H. Ugurlu, P. Cabrera Casarotto, L. Levanov, K. Saksela, O. Vapalahti, E. Castren
This study tests antidepressants and antipsychotics against SARS-CoV-2 pseudoviruses and finds fluoxetine inhibits infection, including against variants with spike mutations.
bioRxiv · Mar 22, 2021Pharmacology & Toxicology