Author

L. Levanov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

O. Vapalahti· 4 shared H. Ugurlu· 2 shared J. Hepojoki· 2 shared K. Saksela· 2 shared S. Kuivanen· 2 shared A. Haveri· 1 shared A. Helenius· 1 shared A. Kipar· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

O. Vapalahti

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Intranasal inhibitor broadly blocks SARS-CoV-2 including recent highly immunoevasive Omicron subvariants

A. R. Mäkelä, H. Ugurlu, L. Hannula, P. Salminen, R. Kant, R. Fagerlund, S. Mäki, A. Haveri, T. Strandin, L. Kareinen, J. Hepojoki, L. Levanov, A. Pasternack, R. A. Naves, O. Ritvos, , K. Saksela

This paper describes a novel intranasal inhibitor, TriSb92, that effectively neutralizes SARS-CoV-2 and recent Omicron subvariants, offering protection against infection in mice.

bioRxiv · Dec 28, 2021 · PreprintMicrobiology

Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine show antiviral activity against the novel variants in vitro

M. S. Fred, S. Kuivanen, H. Ugurlu, P. Cabrera Casarotto, L. Levanov, K. Saksela, O. Vapalahti, E. Castren

This study tests antidepressants and antipsychotics against SARS-CoV-2 pseudoviruses and finds fluoxetine inhibits infection, including against variants with spike mutations.

bioRxiv · Mar 22, 2021Pharmacology & Toxicology

Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system

L. Cantuti-Castelvetri, R. Ohja, L. Pedro, M. Djannatian, J. Franz, S. Kuivanen, K. Kallio, T. Kaya, M. Anastasina, T. Smura, L. Levanov, L. Szirovicza, A. Tobi, H. Kallio-Kokko, P. Osterlund, , M. Simons

This study shows that neuropilin-1 enhances SARS-CoV-2 infectivity and facilitates viral entry into the central nervous system via the olfactory pathway.

bioRxiv · Jun 7, 2020Microbiology

Defining of MAbs-neutralizing sites on the surface glycoproteins Gn and Gc of a hantavirus using vesicular stomatitis virus pseudotypes and site-directed mutagenesis

L. Levanov, R. P. Iheozor-Ejiofor, A. Lundkvist, O. Vapalahti, A. Plyusnin

The paper identifies neutralizing epitopes on hantavirus glycoproteins using pseudotyped VSV particles and site-directed mutagenesis, showing specific amino acid residues critical for antibody neutralization.

bioRxiv · Apr 26, 2018Microbiology