Role of TLR4 in persistent Leptospira interrogans infection: a comparative in vivo study in mice
N. Nair, M. S. Guedes, A. Hajjar, C. Werts, M. Gomes-Solecki
This study investigates the role of TLR4 in leptospirosis by comparing infection outcomes in humanized TLR4 mice, wild-type mice, and TLR4-deficient mice, finding that human TLR4 does not increase susceptibility to infection.
bioRxiv · Jun 15, 2020 · PreprintMicrobiology