Author

A. Hajjar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. M. Brown· 2 shared A. Cheng· 1 shared A. Dimas· 1 shared A. E. Carpenter· 1 shared A. H. Lopez-Yglesias· 1 shared A. J. Horak· 1 shared A. J. Verster· 1 shared A. Lee· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

J. M. Brown

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

nELISA: A high-throughput, high-plex platform enables quantitative profiling of the inflammatory secretome

M. Dagher, G. Ongo, N. Robichaud, J. Kong, W. Rho, I. Teahulos, A. Tavakoli, S. Bovaird, S. Merjaneh, A. Tan, K. Edwardson, C. Scheepers, A. Ng, A. Hajjar, B. Sow, , D. Juncker

nELISA enables high-throughput, high-plex protein profiling of the inflammatory secretome, revealing 447 significant cytokine responses across multiple donors and conditions.

bioRxiv · Apr 17, 2023 · PreprintBioengineering

Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome

M. Wang, L. J. Osborn, S. Jain, X. Meng, A. Weakley, J. Yan, W. Massey, V. Venkateshwari, A. J. Horak, R. Banerjee, D. S. Allende, R. Chan, A. Hajjar, A. Dimas, A. Zhao, , M. A. Fischbach

The paper investigates how strain dropouts in the gut microbiome affect community metabolism and host physiology, finding that functionally redundant strains can have significant impacts outside their niche.

bioRxiv · Jul 25, 2022Microbiology

Nlrc4 inflammasome is critical for host protection against flagellated Salmonella

A. H. Lopez-Yglesias, C.-C. Lu, M. A. Lai, E. Quarles, X. Zhao, A. Hajjar, K. D. Smith

This study shows that Nlrc4 inflammasome recognition of Salmonella flagellin is critical for mucosal immunity but not systemic infection.

bioRxiv · May 13, 2022 · PreprintImmunology

Disruption of the gut microbiota attenuates epithelial ovarian cancer sensitivity to cisplatin therapy

L. Chambers, E. L. Esakov, C. Braley, L. Trestan, Z. Alali, D. Bayik, J. Lathia, N. Sangwan, P. Bazeley, A. S. Joehlin-Price, M. Dwidar, A. Hajjar, P. P. Ahern, J. Claesen, P. Rose, , O. Reizes

This study shows that antibiotic treatment disrupts the gut microbiome, leading to increased resistance to cisplatin in ovarian cancer models.

bioRxiv · Jun 16, 2020 · PreprintCancer Biology

Role of TLR4 in persistent Leptospira interrogans infection: a comparative in vivo study in mice

N. Nair, M. S. Guedes, A. Hajjar, C. Werts, M. Gomes-Solecki

This study investigates the role of TLR4 in leptospirosis by comparing infection outcomes in humanized TLR4 mice, wild-type mice, and TLR4-deficient mice, finding that human TLR4 does not increase susceptibility to infection.

bioRxiv · Jun 15, 2020 · PreprintMicrobiology

Acquired interbacterial defense systems protect against interspecies antagonism in the human gut microbiome

B. D. Ross, A. J. Verster, M. C. Radey, D. T. Schmidtke, C. E. Pope, L. R. Hoffman, A. Hajjar, S. B. Peterson, E. Borenstein, J. Mougous

bioRxiv · Jul 11, 2019Microbiology