Author

N. Nair

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

M. Gomes-Solecki· 3 shared J. F. Azevedo· 2 shared K. Samanta· 2 shared A. Hajjar· 1 shared A. Oubrie· 1 shared A. Papanicolau-Sengos· 1 shared A. Sahu· 1 shared B. Jansen· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersMicrobiology

M. Gomes-Solecki

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues

N. Sanghvi, C. Calvo-Alcaniz, P. Rajagopal, S. Scalera, V. Canu, S. Sinha, F. Schischlik, K. Wang, S. Madan, E. Shulman, A. Papanicolau-Sengos, G. Blandino, E. Ruppin, N. Nair

The paper compares gene expression in primary and metastatic tumors to their origin and target tissues, finding metastases more resemble target tissues and show reduced cancer hallmark activity.

bioRxiv · Oct 30, 2023Cancer Biology

Infected I. scapularis nymphs maintained in prolonged questing under optimal environmental conditions for one year can transmit B. burgdorferi to uninfected hosts

K. Samanta, J. F. Azevedo, N. Nair, S. Kundu, M. Gomes-Solecki

bioRxiv · Apr 14, 2022 · PreprintMicrobiology

Data-driven discovery of targets for bipotent anticancer drugs identifies Estrogen Related Receptor Alpha

A. Sahu, X. Wang, P. Munson, J. Klomp, X. Wang, S. Gu, G. Qian, P. Nicol, Z. Zeng, C. Wang, C. Tokheim, W. Zhang, J. Fu, J. Wang, N. Nair, , K. Flaherty

BipotentR identifies immune-metabolic regulators for bipotent anticancer drugs, demonstrating ESRRA inhibition's effects on tumor metabolism and immune mechanisms.

bioRxiv · Oct 25, 2021 · PreprintCancer Biology

Maternal transfer of neutralizing antibodies to OspA after oral vaccination of the rodent reservoir

K. O'Connell, N. Nair, K. Samanta, J. F. Azevedo, G. D. Brown, C. A. Petersen, M. Gomes-Solecki

The paper shows that oral vaccination of mice leads to maternal transfer of neutralizing anti-OspA antibodies to pups via colostrum, with antibody persistence lasting up to 9 weeks.

bioRxiv · Jan 27, 2021Microbiology

Role of TLR4 in persistent Leptospira interrogans infection: a comparative in vivo study in mice

N. Nair, M. S. Guedes, A. Hajjar, C. Werts, M. Gomes-Solecki

This study investigates the role of TLR4 in leptospirosis by comparing infection outcomes in humanized TLR4 mice, wild-type mice, and TLR4-deficient mice, finding that human TLR4 does not increase susceptibility to infection.

bioRxiv · Jun 15, 2020 · PreprintMicrobiology