Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr mice
D. M. Rohraff, Y. He, E. A. Farkash, M. Schonfeld, P.-S. Tsou, A. H. Sawalha
This study shows that inhibiting EZH2 reduces lupus-like disease in MRL/lpr mice by improving survival and decreasing anti-dsDNA antibodies and inflammation.
bioRxiv · Dec 25, 2018Immunology