Author

A. H. Sawalha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. Schonfeld· 2 shared P.-S. Tsou· 2 shared B. Miglioranza Scavuzzi· 1 shared C. E. Strohlein· 1 shared D. M. Rohraff· 1 shared E. A. Farkash· 1 shared E. Gensterblum-Miller· 1 shared F. W. Miller· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

M. Schonfeld

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 21, 2022

Ezh2 knockout in B cells impairs plasmablast differentiation and ameliorates lupus-like disease in MRL/lpr mice

X. Zheng, M. G. Dozmorov, C. E. Strohlein…·A. H. Sawalha

This study shows that deleting EZH2 in B cells reduces autoantibody production and improves lupus-like disease in MRL/lpr mice by impairing plasmablast differentiation.

DOI 10.1101/2022.07.21.500990

mousescRNA-seq

𝕏 PostBluesky

ImmunologybioRxivAug 25, 2020

Antigen Presentation-Independent Reciprocal Immune Modulation by HLA-DRB1 Allelic Epitopes that Associate with Autoimmune Disease Risk or Protection

V. van Drongelen, B. Miglioranza Scavuzzi, S. Veloso Nogueira…·J. Holoshitz

The paper shows HLA-DRB1 alleles influence macrophage polarization independently of antigen presentation, affecting inflammatory responses linked to autoimmune disease risk or protection.

DOI 10.1038/s41598-021-82195-3

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivDec 25, 2018

Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr mice

D. M. Rohraff, Y. He, E. A. Farkash…·A. H. Sawalha

This study shows that inhibiting EZH2 reduces lupus-like disease in MRL/lpr mice by improving survival and decreasing anti-dsDNA antibodies and inflammation.

DOI 10.1002/art.40931

mouseflow cytometry

𝕏 PostBluesky

ImmunologybioRxivAug 22, 2018

Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells

S. Miller, P. Coit, E. Gensterblum-Miller…·A. H. Sawalha

This study identifies hypomethylation of STAT1 and HLA-DRB1 in lupus CD8+ T cells, linking it to type-I interferon-dependent HLA-DRB1 expression and immune activation.

DOI 10.1136/annrheumdis-2018-214323

humanDNA methylation

𝕏 PostBluesky