Author

P.-S. Tsou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. H. Sawalha· 2 shared A. Sawalha· 2 shared D. M. Rohraff· 2 shared M. Schonfeld· 2 shared D. A. Fox· 1 shared D. Khanna· 1 shared E. A. Farkash· 1 shared E. Gensterblum-Miller· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. H. Sawalha

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of histone readers bromodomain extra-terminal proteins alleviates skin fibrosis in experimental models of scleroderma

S. Vichaikul, M. Gurrea-Rubio, M. A. Amin, P. L. Campbell, Q. Wu, M. N. Mattichak, W. D. Brodie, P. J. Palisoc, M. Ali, S. Muraoka, J. H. Ruth, E. N. Model, D. M. Rohraff, J. L. Hervoso, Y. Mao-Draayer, , P.-S. Tsou

This study shows that inhibiting BET proteins, particularly BRD4, reduces skin fibrosis in scleroderma models by affecting calcium signaling and gene expression.

bioRxiv · Aug 7, 2020Pharmacology & Toxicology

Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr mice

D. M. Rohraff, Y. He, E. A. Farkash, M. Schonfeld, P.-S. Tsou, A. H. Sawalha

This study shows that inhibiting EZH2 reduces lupus-like disease in MRL/lpr mice by improving survival and decreasing anti-dsDNA antibodies and inflammation.

bioRxiv · Dec 25, 2018Immunology

Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells

S. Miller, P. Coit, E. Gensterblum-Miller, P. Renauer, N. C. Kilian, M. Schonfeld, P.-S. Tsou, A. H. Sawalha

This study identifies hypomethylation of STAT1 and HLA-DRB1 in lupus CD8+ T cells, linking it to type-I interferon-dependent HLA-DRB1 expression and immune activation.

bioRxiv · Aug 22, 2018Immunology

Caffeine downregulates inflammatory pathways involved in autoimmunity

M. Iris, P.-S. Tsou, A. Sawalha

This study shows caffeine reduces inflammatory gene expression and cytokine levels in PBMCs, suggesting potential therapeutic effects in autoimmune diseases.

bioRxiv · Dec 31, 2017Immunology