Author

M. Sehgal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 5 Research Focus:differential expression· 5 Research Focus:gene regulatory network inference· 5 Organism:human· 5 Approach:statistical model· 5 Research Focus:cell type annotation· 4 Assay:scRNA-seq· 4 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

M. K. Jolly· 5 shared J. M. Vaz· 2 shared J. Somarelli· 2 shared S. Muralidharan· 2 shared S. R· 2 shared A. Armstrong· 1 shared A. Nanda· 1 shared A. Saha· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersCancer Biology

M. K. Jolly

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma

M. Sehgal, S. P. Nayak, S. Sahoo, J. Somarelli, M. K. Jolly

The paper identifies mutually exclusive gene regulation patterns between noradrenergic and mesenchymal states in neuroblastoma, linking them to phenotypic plasticity and therapy resistance.

bioRxiv · Sep 3, 2023Cancer Biology

Characterizing heterogeneity along EMT and metabolic axes in colorectal cancer reveals underlying consensus molecular subtype-specific trends

M. Sehgal, S. R, J. M. Vaz, Y. Raja G, S. Muralidharan, S. Venkatraghavan, M. K. Jolly

The paper analyzes CRC subtypes to show how EMT and metabolic axes vary across CMS subtypes, revealing subtype-specific metabolic and mesenchymal correlations.

bioRxiv · Aug 6, 2023Cancer Biology

Emergent dynamics of underlying regulatory network links EMT and androgen receptor-dependent resistance in prostate cancer

R. Jindal, A. Nanda, M. Pillai, K. Ware, D. Singh, M. Sehgal, A. Armstrong, J. Somarelli, M. K. Jolly

The paper models a regulatory network linking EMT and AR resistance in prostate cancer, identifying four phenotypes and showing stochastic switching between states.

Computational and Structural Biotechnology Journal · Jan 1, 2023Peer-reviewedCancer Biology

PD-L1 activity is associated with partial EMT and metabolic reprogramming in carcinomas

S. Muralidharan, M. Sehgal, S. R, S. Mandal, S. S. Majumdar, Y. M, A. Saha, M. K. Jolly

The paper identifies a link between PD-L1 activity, partial EMT, and metabolic reprogramming in carcinomas using transcriptomic data and single-cell RNA-seq.

bioRxiv · Oct 5, 2022Cancer Biology

Partial EMT and associated changes in cellular plasticity in oncovirus-positive samples

M. Sehgal, R. Ray, J. M. Vaz, S. Kanikar, J. A. Somarelli, M. K. Jolly

The paper analyzes transcriptomics data to identify common gene regulatory features in oncovirus-positive samples, revealing partial EMT and metabolic changes linked to immune checkpoint molecules.

bioRxiv · Aug 20, 2022Cancer Biology