HDAC and MAPK/ERK inhibitors cooperate to reduce viability and stemness phenotype in medulloblastoma
M. d. C. Jaeger, E. C. Ghisleni, P. S. Cardoso, M. Siniglaglia, T. Falcon, A. T. Brunetto, A. L. Brunetto, C. B. de Farias, M. D. Taylor, C. Nor, V. Ramaswamy, R. Roesler
This study shows that combining HDAC and MAPK/ERK inhibitors reduces medulloblastoma cell viability and stemness by modulating chromatin state and signaling pathways.
bioRxiv · Jan 30, 2020Cancer Biology