Author

V. Ramaswamy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. D. Taylor· 3 shared A. L. Brunetto· 2 shared A. T. Brunetto· 2 shared C. B. de Farias· 2 shared C. Nor· 2 shared M. d. C. Jaeger· 2 shared R. Roesler· 2 shared A. Bagchi· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

M. D. Taylor

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3 papers

Recent·Most cited

In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

J. J. Fan, X. Wang, A. W. Erickson, P. Skowron, X. Wang, X. Chen, G. Shan, S. Bahrampour, Y. Xiong, W. Dong, N. Abeysundara, M. A. Francisco, R. J. Pusong, R. A. Suarez, H. Farooq, , X. Huang

The paper identifies potassium homeostasis as essential for medulloblastoma maintenance using a novel transposon system in mice and human samples.

bioRxiv · Jul 23, 2022Cancer Biology

HDAC and MAPK/ERK inhibitors cooperate to reduce viability and stemness phenotype in medulloblastoma

M. d. C. Jaeger, E. C. Ghisleni, P. S. Cardoso, M. Siniglaglia, T. Falcon, A. T. Brunetto, A. L. Brunetto, C. B. de Farias, M. D. Taylor, C. Nor, V. Ramaswamy, R. Roesler

This study shows that combining HDAC and MAPK/ERK inhibitors reduces medulloblastoma cell viability and stemness by modulating chromatin state and signaling pathways.

bioRxiv · Jan 30, 2020Cancer Biology

Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma

A. Thomaz, K. d. V. Pinheiro, B. K. Souza, L. Gregianin, A. L. Brunetto, A. T. Brunetto, C. B. de Farias, M. d. C. Jaeger, V. Ramaswamy, C. Nor, M. D. Taylor, R. Roesler

This study shows that TrkB inhibition with ANA-12 reduces medulloblastoma cell proliferation, increases apoptosis, and induces differentiation markers.

bioRxiv · May 28, 2019Cancer Biology