Author

M. Sirajuddin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Assay:cryo-EM· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

P. Lama· 3 shared S. Kesarwani· 3 shared A. Chandra· 2 shared D. Dileep· 2 shared A. Dungdung· 1 shared A. Jijumon· 1 shared A. Kumari· 1 shared B. M. Rao· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersCell Biology

P. Lama

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Doublet microtubule inner junction protein FAP20 recruits tubulin to the microtubule lattice

M. Bangera, A. Dungdung, S. Prabhu, M. Sirajuddin

This study shows FAP20 recruits tubulin to microtubules, mediating lateral interactions and contributing to doublet microtubule assembly.

bioRxiv · Nov 25, 2022Biophysics

Myofiber reconstruction at micron scale reveals longitudinal bands in heart ventricular walls

D. Dileep, T. A. Syed, T. F. W. Sloan, D. Perundurai, K. Siddiqi, M. Sirajuddin

The paper reconstructs myofibers in mouse ventricular walls at micron scale, revealing longitudinal fiber bands orthogonal to circumferential ones.

bioRxiv · May 12, 2022 · PreprintCell Biology

Peptide derived nanobody inhibits entry of SARS-CoV-2 variants

N. Mendon, R. A. Ganie, S. Kesarwani, D. Dileep, S. Sasi, P. Lama, A. Chandra, M. Sirajuddin

The paper identifies a nanobody that inhibits SARS-CoV-2 entry by targeting a peptide from the spike protein's receptor-binding motif, showing efficacy against multiple variants.

bioRxiv · Apr 21, 2022 · PreprintCell Biology

Initiation of ensemble kinesin-3 motility is regulated by the rigidity of cargo-motor attachment

P. Lama, M. Sirajuddin

This study shows that the rigidity of cargo-motor linkers affects the ability of kinesin-3 motors to engage with microtubule tracks during ensemble transport.

bioRxiv · Dec 2, 2021 · PreprintBiochemistry

Genetically encoded live cell sensor for tyrosinated microtubules

S. Kesarwani, P. Lama, A. Chandra, P. P. Reddy, A. Jijumon, S. Bodakuntla, B. M. Rao, C. Janke, R. Das, M. Sirajuddin

The paper develops a genetically encoded live cell sensor for tyrosinated microtubules and uses it to study drug-induced microtubule depolymerization.

bioRxiv · Mar 29, 2020Cell Biology

Structural insights into filament recognition by cellular actin markers

A. Kumari, S. Kesarwani, M. G. Javoor, K. R. Vinothkumar, M. Sirajuddin

The paper presents cryo-EM structures of phalloidin, lifeAct, and utrophin bound to F-actin, revealing their binding mechanisms and informing marker selection for actin studies.

bioRxiv · Nov 18, 2019Cell Biology