The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection
N. Anikeeva, M. Steblyanko, L. Kuri-Cervantes, M. Buggert, M. R. Betts, Y. Sykulev
The paper examines CD8 T cell immune synapses in chronic HIV infection, finding that naive T cells develop mature synapses and degranulation patterns typically seen in differentiated cells, leading to impaired viral control.
bioRxiv · Jan 13, 2022Immunology