Author

L. Kuri-Cervantes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 7

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:experimental assay· 6 Assay:flow cytometry· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:clustering· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2

Frequent Co-Authors

M. R. Betts· 6 shared A. E. Baxter· 4 shared A. Pattekar· 4 shared D. Mathew· 4 shared J. Dougherty· 4 shared M. E. Weirick· 4 shared O. Kuthuru· 4 shared S. Gouma· 4 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersImmunology

M. R. Betts

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Author profile →

7 papers

Recent·Most cited

The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection

N. Anikeeva, M. Steblyanko, L. Kuri-Cervantes, M. Buggert, M. R. Betts, Y. Sykulev

The paper examines CD8 T cell immune synapses in chronic HIV infection, finding that naive T cells develop mature synapses and degranulation patterns typically seen in differentiated cells, leading to impaired viral control.

bioRxiv · Jan 13, 2022Immunology

mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern

R. R. Goel, M. M. Painter, S. A. Apostolidis, D. Mathew, W. Meng, A. M. Rosenfeld, K. A. Lundgreen, A. Reynaldi, D. S. Khoury, A. Pattekar, S. Gouma, L. Kuri-Cervantes, P. Hicks, S. Dysinger, A. Hicks, , Set

This study shows that mRNA vaccination generates durable immune memory against SARS-CoV-2 and variants of concern, with continued evolution of B and T cell responses for at least 6 months.

bioRxiv · Aug 23, 2021 · PreprintImmunology

Rapid induction of antigen-specific CD4+ T cells guides coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination

M. M. Painter, D. Mathew, R. R. Goel, S. A. Apostolidis, A. Pattekar, O. Kuthuru, A. E. Baxter, R. S. Herati, D. A. Oldridge, S. Gouma, P. Hicks, S. Dysinger, K. A. Lundgreen, L. Kuri-Cervantes, S. Adamski, , E. J. Wherry

This study shows that mRNA vaccination rapidly induces antigen-specific CD4+ T cells, which coordinate humoral and cellular immune responses, with booster doses enhancing T cell responses in naive individuals.

bioRxiv · Apr 21, 2021 · PreprintImmunology

The identity of human tissue-emigrant CD8+ T cells

M. Buggert, L. A. Vella, S. Nguyen, V. Wu, T. Sekine, A. Perez-Potti, C. R. Maldini, S. Manne, S. Darko, A. Ransier, L. Kuri-Cervantes, A. Sada Japp, I. Bukh Brody, M. A. Ivarsson, L. Hertwig, , M. R. Betts

The paper characterizes tissue-emigrant CD8+ T cells in humans and non-human primates, revealing distinct migratory behaviors and clonal dynamics.

bioRxiv · Aug 11, 2020Immunology

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

D. Mathew, J. R. Giles, A. E. Baxter, A. R. Greenplate, J. E. Wu, C. Alanio, D. A. Oldridge, L. Kuri-Cervantes, M. B. Pampena, K. D'Andrea, S. Manne, Z. Chen, Y. J. Huang, J. P. Reilly, A. R. Weisman, , E. J. Wherry

The paper identifies distinct immunotypes in COVID-19 patients through high-dimensional cytometry, linking them to disease severity and potential therapeutic implications.

bioRxiv · May 20, 2020Immunology

Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection

L. Kuri-Cervantes, M. B. Pampena, W. Meng, A. M. Rosenfeld, C. A. G. Ittner, A. R. Weisman, R. Agyekum, D. Mathew, A. E. Baxter, L. Vella, O. Kuthuru, S. Apostolidis, L. Bershaw, J. Dougherty, A. R. Greenplate, , M. R. Betts

The paper identifies broad immune perturbations in severe COVID-19, including innate and adaptive immune cell changes and heterogeneity in B cell responses and antibody production.

bioRxiv · May 18, 2020 · PreprintImmunology

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects

M. M. Klicznik, P. A. Morawski, B. Höllbacher, S. Varkhande, S. Motley, L. Kuri-Cervantes, E. Goodwin, M. D. Rosenblum, S. A. Long, G. Brachtl, T. Duhen, M. Betts, D. Campbell, I. K. Gratz

The paper identifies human CD4+CD103+ cutaneous resident memory T cells in circulation and shows they can migrate to distant skin sites.

bioRxiv · Mar 14, 2019 · PreprintImmunology