Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
V. H. Wu, S. Nguyen, J. M. L. Nordin, J. Joy, F. Mampe, P. Tebas, L. J. Montaner, K. J. Bar, L. A. Vella, M. R. Betts
This study identifies phenotypic and epigenetic heterogeneity in the HIV-1 infected CD4+ T cell reservoir using single-cell multiomic profiling of ART-treated individuals.
bioRxiv · Apr 2, 2022Microbiology
N. Anikeeva, M. Steblyanko, L. Kuri-Cervantes, M. Buggert, M. R. Betts, Y. Sykulev
The paper examines CD8 T cell immune synapses in chronic HIV infection, finding that naive T cells develop mature synapses and degranulation patterns typically seen in differentiated cells, leading to impaired viral control.
bioRxiv · Jan 13, 2022Immunology
R. R. Goel, M. M. Painter, S. A. Apostolidis, D. Mathew, W. Meng, A. M. Rosenfeld, K. A. Lundgreen, A. Reynaldi, D. S. Khoury, A. Pattekar, S. Gouma, L. Kuri-Cervantes, P. Hicks, S. Dysinger, A. Hicks, , Set
This study shows that mRNA vaccination generates durable immune memory against SARS-CoV-2 and variants of concern, with continued evolution of B and T cell responses for at least 6 months.
bioRxiv · Aug 23, 2021 · PreprintImmunology
M. M. Painter, D. Mathew, R. R. Goel, S. A. Apostolidis, A. Pattekar, O. Kuthuru, A. E. Baxter, R. S. Herati, D. A. Oldridge, S. Gouma, P. Hicks, S. Dysinger, K. A. Lundgreen, L. Kuri-Cervantes, S. Adamski, , E. J. Wherry
This study shows that mRNA vaccination rapidly induces antigen-specific CD4+ T cells, which coordinate humoral and cellular immune responses, with booster doses enhancing T cell responses in naive individuals.
bioRxiv · Apr 21, 2021 · PreprintImmunology
N. Zabaleta, W. Dai, U. Bhatt, J. A. Chichester, J. Sanmiguel, R. Estelien, K. T. Michalson, C. Diop, D. Maciorowski, W. Qi, E. Hudspeth, A. Cucalon, C. D. Dyer, M. B. Pampena, J. J. Knox, , L. H. Vandenberghe
This paper evaluates an AAV-based COVID-19 vaccine in mice and non-human primates, showing sustained neutralizing antibodies and memory T-cells, with room-temperature stability and scalable production.
bioRxiv · Jan 5, 2021 · PreprintImmunology
M. Buggert, L. A. Vella, S. Nguyen, V. Wu, T. Sekine, A. Perez-Potti, C. R. Maldini, S. Manne, S. Darko, A. Ransier, L. Kuri-Cervantes, A. Sada Japp, I. Bukh Brody, M. A. Ivarsson, L. Hertwig, , M. R. Betts
The paper characterizes tissue-emigrant CD8+ T cells in humans and non-human primates, revealing distinct migratory behaviors and clonal dynamics.
bioRxiv · Aug 11, 2020Immunology
D. Mathew, J. R. Giles, A. E. Baxter, A. R. Greenplate, J. E. Wu, C. Alanio, D. A. Oldridge, L. Kuri-Cervantes, M. B. Pampena, K. D'Andrea, S. Manne, Z. Chen, Y. J. Huang, J. P. Reilly, A. R. Weisman, , E. J. Wherry
The paper identifies distinct immunotypes in COVID-19 patients through high-dimensional cytometry, linking them to disease severity and potential therapeutic implications.
bioRxiv · May 20, 2020Immunology
L. Kuri-Cervantes, M. B. Pampena, W. Meng, A. M. Rosenfeld, C. A. G. Ittner, A. R. Weisman, R. Agyekum, D. Mathew, A. E. Baxter, L. Vella, O. Kuthuru, S. Apostolidis, L. Bershaw, J. Dougherty, A. R. Greenplate, , M. R. Betts
The paper identifies broad immune perturbations in severe COVID-19, including innate and adaptive immune cell changes and heterogeneity in B cell responses and antibody production.
bioRxiv · May 18, 2020 · PreprintImmunology
S. A. Overall, J. S. Toor, S. Hao, M. Yarmarkovich, S. Nguyen, A. S. Japp, D. Moschidi, M. R. Betts, J. M. Maris, P. Smibert, N. G. Sgourakis
The paper introduces a method to produce pMHC-I tetramer libraries using TAPBPR chaperone-mediated peptide exchange, enabling high-throughput analysis of TCR repertoires and pMHC-I specificities.
bioRxiv · May 30, 2019Immunology