Author

M. Stratigopoulou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. E. Guikema· 2 shared R. J. Bende· 2 shared A. Pelissier· 1 shared B. Pilzecker· 1 shared C. J. M. van Noesel· 1 shared C. J. van Noesel· 1 shared E. Dimitriadis· 1 shared H. E. Jacobs· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersEvolutionary Biology

J. E. Guikema

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2 papers

Recent·Most cited

Convergent Evolution and B-Cell Recirculation in Germinal Centers in a Human Lymph Node

A. Pelissier, M. Stratigopoulou, N. Donner, E. Dimitriadis, R. J. Bende, J. E. Guikema, M. R. Martinez, C. J. M. van Noesel

The paper analyzes B-cell clonal diversity and evolution in human germinal centers using LCM and Rep-seq, finding convergent evolution and shared antigen responses across GCs.

bioRxiv · Nov 9, 2022Evolutionary Biology

DNA polymerase β prevents AID-instigated mutagenic non-canonical mismatch DNA repair

M. Bahjat, M. Stratigopoulou, B. Pilzecker, T. P. van Dam, S. Mobach, R. J. Bende, C. J. van Noesel, H. E. Jacobs, J. E. Guikema

The paper shows that DNA polymerase β degradation in GC B cells leads to mutagenic non-canonical mismatch repair, promoting A:T mutations during somatic hypermutation.

bioRxiv · Jan 30, 2020 · PreprintImmunology