Author

M. T. Cushion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:rat· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Ashbaugh· 2 shared A. Porollo· 2 shared S. G. Sayson· 2 shared A. Ashbauad· 1 shared A. Sukura· 1 shared B. Pahar· 1 shared C. A. Cuomo· 1 shared C. S. Meier· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

A. Ashbaugh

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Pneumocystis murina Promotes Inflammasome Formation and NETosis during Pneumocystis Pneumonia

S. G. Sayson, A. Ashbaugh, A. Porollo, M. T. Cushion

This study identifies NLRP3 inflammasome activation and NETosis in P. murina pneumonia, highlighting neutrophils' role in inflammation and tissue damage.

bioRxiv · Feb 16, 2024 · PreprintImmunology

Extracellular Vesicles from Pneumocystis carinii-Infected Rats Impair Fungal Viability but are Dispensable for Macrophage Functions

S. G. Sayson, A. Ashbaugh, M. T. Cushion

This study isolates and characterizes extracellular vesicles from Pneumocystis-infected rats, showing they impair fungal viability but are not required for macrophage function.

bioRxiv · Sep 19, 2023 · PreprintMicrobiology

Fungal antigenic variation using mosaicism and reassortment of subtelomeric genes' repertoires, potentially mediated by DNA triplexes

C. S. Meier, M. Pagni, S. Richard, K. Muhlethaler, J. M. G. C. F. Almeida, G. Nevez, M. T. Cushion, E. J. Calderon, P. M. Hauser

This paper identifies a novel mechanism of antigenic variation in Pneumocystis jirovecii involving DNA triplex-mediated recombination of subtelomeric genes.

bioRxiv · Mar 21, 2023 · PreprintMicrobiology

Genomic insights into the host specific adaptation of the Pneumocystis genus and emergence of the human pathogen Pneumocystis jirovecii

O. H. Cisse, L. Ma, J. P. Dekker, P. P. Khil, J.-H. Youn, J. M. Brenchley, R. V. Blair, B. Pahar, M. Chabe, K. K. A. Van Rompay, R. Keesler, A. Sukura, V. Hirsch, G. Kutty, Y. Liu, , J. A. Kovacs

The paper sequenced genomes of Pneumocystis species from different mammals to study host specificity and evolutionary adaptations, revealing insights into the emergence of the human pathogen P. jirovecii.

bioRxiv · Jul 29, 2020Evolutionary Biology

The Effects of Sex and Strain on Pneumocystis murina Fungal Burdens in Mice

N. Tisdale, A. Ashbauad, K. Hendricks, M. Collins, A. Porollo, M. T. Cushion

This study shows female mice have higher Pneumocystis murina infection burdens than males at later time points across three strains.

bioRxiv · Sep 26, 2019 · PreprintMicrobiology