Ongoing Production of Tissue-Resident Macrophages from Hematopoietic Stem Cells in Healthy Adult Macaques
A. R. Rahmberg, C. Wu, T. Shin, S. G. Hong, L. Pei, H. D. Hickman, C. E. Dunbar, J. M. Brenchley
This study shows that hematopoietic stem cells continuously replenish tissue-resident macrophages in healthy adult macaques, challenging the notion that all macrophages are derived from yolk sac cells.
bioRxiv · Dec 19, 2022Immunology