Potent macrocycle inhibitors of the human SAGA deubiquitinating module
M. T. Morgan, T. Ikenoue, H. Suga, C. Wolberger
The paper identifies potent cyclic peptide inhibitors of the USP22 subunit in the SAGA DUB module, showing increased H2B monoubiquitination in treated cells.
bioRxiv · May 13, 2021Biochemistry