Phosphorylation of the selective autophagy receptor TAX1BP1 by canonical and noncanonical IκB kinases promotes its lysosomal localization and clearance of MAVS aggregates
Y. B. Choi, J. Zhang, M. T. Vo, J. White, C. He, E. W. Harhaj
This study shows that phosphorylation of TAX1BP1 by IκB kinases promotes its lysosomal degradation and enhances its ability to clear MAVS aggregates.
bioRxiv · Jan 7, 2021 · PreprintImmunology