Highly Multiplexed Genome Engineering Using CRISPR/Cas9 gRNA Arrays
M. Kurata, N. K. Wolf, W. S. Lahr, M. T. Weg, S. Lee, K. Hui, M. Shiraiwa, B. R. Webber, B. Moriarity
This paper develops a CRISPR/Cas9 gRNA array system to enable efficient multiplex genome engineering by delivering up to 10 gRNAs as a single transcript.
bioRxiv · May 25, 2018Bioengineering