Author

B. Moriarity

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

B. R. Webber· 2 shared E. Pomeroy· 2 shared W. S. Lahr· 2 shared A. Cartagena-Rivera· 1 shared A. Zhovmer· 1 shared B. Smeester· 1 shared D. Largaespada· 1 shared D. Odde· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

B. R. Webber

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

E. D. Tabdanov, N. J. Rodriguez-Merced, A. Cartagena-Rivera, V. Puram, M. Callaway, E. Ensminger, E. Pomeroy, K. Yamamoto, W. S. Lahr, B. R. Webber, B. Moriarity, A. Zhovmer, P. Provenzano

This study engineers T cells to improve 3D migration through tumor microenvironments by manipulating microtubule stability and contractility, showing enhanced migration in 3D matrices and tumors.

bioRxiv · Apr 21, 2020Cancer Biology

SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis

B. Smeester, N. Slipek, E. Pomeroy, H. Bomberger, G. Shamsan, J. Peterson, M. Crosby, G. Draper, K. Becklin, E. Rahrmann, J. McCarthy, D. Odde, D. Wood, D. Largaespada, B. Moriarity

This study shows SEMA4C promotes osteosarcoma growth and metastasis, with its inhibition reducing tumor progression and suggesting clinical potential.

bioRxiv · Jan 14, 2019Cancer Biology

Highly Multiplexed Genome Engineering Using CRISPR/Cas9 gRNA Arrays

M. Kurata, N. K. Wolf, W. S. Lahr, M. T. Weg, S. Lee, K. Hui, M. Shiraiwa, B. R. Webber, B. Moriarity

This paper develops a CRISPR/Cas9 gRNA array system to enable efficient multiplex genome engineering by delivering up to 10 gRNAs as a single transcript.

bioRxiv · May 25, 2018Bioengineering