Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications
M. Touceda-Suarez, E. M. Kita, R. D. Acemel, P. N. Firbas, M. S. Magri, S. Naranjo, J. J. Tena, J. L. Gomez-Skarmeta, I. Maeso, M. Irimia
The paper shows that ancient genomic regulatory blocks (GRBs) were maintained as single copies in humans after vertebrate whole genome duplications, with their duplicated copies dismantled to form gene deserts.
bioRxiv · Sep 25, 2019Evolutionary Biology