Integrated gut-liver-on-a-chip platform as an in vitro human model of non-alcoholic fatty liver disease
J. Yang, Y. Hirai, K. Iida, S. Ito, M. Trumm, S. Terada, R. Sakai, T. Tsuchiya, O. Tabata, K.-i. Kamei
The paper develops a gut-liver-on-a-chip platform to model NAFLD and shows co-culturing gut and liver cells alters gene expression and lipid accumulation in response to free fatty acids.
bioRxiv · Jun 10, 2020 · PreprintBioengineering