SARS-CoV-2 Spike evolution influences GBP and IFITM sensitivity
D. Mesner, A.-K. Reuschl, M. V. X. Whelan…·C. Jolly
This study shows that SARS-CoV-2 variants differ in their sensitivity to GBP and IFITM restriction factors, with Omicron uniquely restricted by these factors due to changes in its spike protein.